Publications

Google Scholar Profile
† These authors contributed equally.

Publications
Korah, M.; Reveron-Thornton, R.F.; Fallah, M.; Xie, P.Y.; Goncalves, A.; Guo, C.; Agolia, J.P.; Delitto, A.E.; Flojo, R.A.B.; Reddy, B.; Yip, K.A.; Lu, J.M.; Tomasso, A.; Tabora, A.D.; Guo, J.L.; Bauer-Rowe, K.E.; Pham, B.; Goyal, L.; Kirane, A.R.; Charville, G.W.; Chaudhuri, O.; Dua, M.M.; Visser, B.C.; Lee, B.; Poultsides, G.A.; Wan, D.C.; Norton, J.A.; Foster, D.S.; Longaker, M.T.; Delitto, D. (2025). “Disruption of Fibroblast MYD88 Signaling Promotes Antitumor Immunity in Pancreatic Ductal Adenocarcinoma.” Cell Reports. DOI: 10.1016/j.celrep.2025.116347.

Griffin, M.F.†; Guo, J.L.†; Parker, J.B.L.; Kuhnert, M.; Li, D.J.; Valencia, C.; Morgan, A.; Downer, M.; Cotterell, A.C.; Lu, J.M.; Dilorio, S.; Bauer-Rowe, K.E.; Januszyk, M.; Chang, H.Y.; Wan, D.C.; Longaker, M.T. (2025). “Multi-Omic Analysis Reveals Retinoic Acid Molecular Drivers for Dermal Fibrosis and Regenerative Repair in the Skin.” Cell Stem Cell. DOI: 10.1016/j.stem.2025.07.010.

Yohei, A.; Spann, N.J.; Tang, W.; Zeng, F.; Seymour, C.; Jansky, S.; Guo, J.L.; Huff, R.; Chanthavixay, K.; Richard, J.L.C.; Mooney, M.; Dhar, D.; Ganguly, S.; Lopez, D.M.; Longaker, M.T.; Benner, C.; Glass, C.K.; Sajti, E. (2025). “Genetic Variation in the Activity of a TREM2-p53 Signaling Axis Determines Oxygen-Induced Lung Injury.” Nature Immunology. DOI: 10.1038/s41590-025-02217-4.

Guo, J.L.†; Griffin, M.F.†; Yoon, J.K.†; Lopez, D.M.; Zhu, Y.; Lu, J.M.; Mikos, G.; Parker, J.B.L.; Mascharak, S.; Brenac, C.; Guardino, N.J.; Abbas, D.B.; Li, D.J.; Valencia, C.; Liang, N.E.; Lu, J.M.; Januszyk, M.; Chang, H.Y.; Wan, D.C.; Desai, T.J.; Longaker, M.T. (2025). “Histological Signatures Map Anti-Fibrotic Factors in Mouse and Human Lungs.” Nature. DOI: 10.1038/s41586-025-08727-3.

Griffin, M.F.; Cook, J.; Morgan, A.; Boffelli, D.; Downer, M.; Spielman, A.F.; Guardino, N.J.; Guo, J.L.; Parker, J.B.L.; Januszyk, M.; Valencia, C.; Kuhnert, M.; Lu, J.M.; Zwick, R.; Wan, D.C.; Klein, O.D.; Longaker, M.T. (2025). “Growth Arrest Specific–6 and Angiotoxin Receptor–Like Signaling Drive Oral Regenerative Wound Repair.” Science Translational Medicine. DOI: 10.1126/scitranslmed.adk2101.

Foster, D.S.†; Guo, J.L.†; Meany, E.; Berry, C.E.; Fallah, M.; Januszyk, M.; Bauer-Rowe, K.E.; Lopez, D.M.; Song, R.; Williams, C.M.; Griffin, M.; Kim, A.; Chinta, M.S.; Marshall, C.D.; Wan, D.C.; Hyun, J.; Wernig, G.; Norton, J.A.; Appel, E.A.; Delitto, D.J.; Longaker, M.T. (2025). “Sustained-Release Anti-JUN Therapeutic Abrogates Post-Operative Adhesions.” Science Translational Medicine. DOI: 10.1126/scitranslmed.adp9957.

Griffin, M.F.; Parker, J.B.L.; Tevlin, R.; Liang, N.E.; Valencia, C.; Morgan, A.; Kuhnert, M.; Downer, M.; Meany, E.L.; Guo, J.L.; Henn, D.; Navarro, R.S.; Shefren, K.; Nguyen, D.; Gurtner, G.C.; Heilshorn, S.C.; Chan, C.K.F.; Januszyk, M.; Appel, E.A.; Momeni, A.; Wan, D.C.; Longaker, M.T. (2025). “Osteopontin Attenuates the Foreign-Body Response to Silicone Implants.” Nature Biomedical Engineering. DOI: 10.1038/s41551-025-01361-4.

Mascharak, S.; Griffin, M.F.; Talbott; H.E.; Guo, J.L.; Davitt, M.F.; Guardino, N.J.; Deleon, N.; Lavin, C.V.; Adem, S.; Khan, A.; Chen, K.; Henn, D.; Spielman, A.F.; Parker, J.; Cotterell, A.C.; Akras, D.; Downer, M.A.; Tevlin, R.; Lorenz, H.P.; Gurtner, G.C.; Januszyk, M.; Wan, D.C. (2025). “Inhibiting Mechanotransduction Prevents Scarring and Yields Regeneration in a Large Animal Model.” Science Translational Medicine. DOI: 10.1126/scitranslmed.adt6387.

Brenac, C.; Fazilat, A.Z.; Fallah, M.; Kawamoto-Duran, D.; Sunwoo, P.S.; Longaker, M.T.; Wan, D.C.; Guo, J.L. (2024). “AI in Plastic Surgery: Customizing Care for Each Patient.” Artificial Intelligence Surgery. DOI: 10.20517/ais.2024.49.

Guo, J.L.; Januszyk, M.; Longaker, M.T. (2024). “Editorial for Special Issue on Artificial Intelligence in Tissue Engineering and Biology.” Tissue Engineering Part A. DOI: 10.1089/ten.tea.2024.024.

Guo, J.L.; Lopez, D.M.; Mascharak, S.; Foster, D.S.; Khan, A.; Davitt, M.F.; Nguyen, A.T.; Burcham, A.R.; Chinta, M.S.; Guardino, N.J.; Griffin, M.; Miller, E.; Januszyk, M.; Raghavan, S.S.; Longacre, T.A.; Delitto, D.J.; Norton, J.A.; Longaker, M.T. (2024). “Hematoxylin and Eosin Architecture Uncovers Clinically Divergent Niches in Pancreatic Cancer.” Tissue Engineering Part A. DOI: 10.1089/ten.tea.2024.0039.

Berry, C.E.; Abbas, D.B.; Griffin, M.; Lintel, H.; Guo, J.L.; Kameni, L.; Churukian, A.A.; Fazilat, A.Z.; Chen, K.; Gurtner, G.C.; Longaker, M.T.; Momeni, A.; Wan, D.C. (2024). “Deferoxamine Topical Cream Superior to Patch in Rescuing Radiation-Induced Fibrosis of Unwounded and Wounded Skin.” Journal of Cellular and Molecular Medicine. DOI: 10.1111/jcmm.18306.

Mascharak, S.†; Guo, J.L.†; Griffin, M.†; Berry, C.E.; Wan, D.C.; Longaker, M.T. (2024). “Modeling and Targeting Mechanical Forces in Organ Fibrosis.” Nature Reviews Bioengineering. DOI: 10.1038/s44222-023-00144-3.

Mascharak, S.†; Guo, J.L.†; Foster, D.S.; Khan, A.; Davitt, M.F.; Nguyen, A.T.; Burcham, A.R.; Chinta, M.S.; Guardino, N.J.; Griffin, M.; Lopez, D.M.; Miller, E.; Januszyk, M.; Raghavan, S.S.; Longacre, T.A.; Delitto, D.J.; Norton, J.A.; Longaker, M.T. (2023). “Desmoplastic Stromal Signatures Predict Patient Outcomes in Pancreatic Ductal Adenocarcinoma.” Cell Reports Medicine. DOI: 10.1016/j.xcrm.2023.101248.
Interviewed on Stanford Medicine News, HemOnc Today.

Berry, C.E.; Downer, M.A.; Morgan, A.G.; Griffin, M.; Liang, N.E.; Kameni, L.; Parker, J.B.L.; Guo, J.L.; Longaker, M.T.; Wan, D.C. (2023). “The Effects of Mechanical Force on Fibroblast Behavior in Cutaneous Injury.” Frontiers in Surgery. DOI: 10.3389/fsurg.2023.1167067.

Guo, J.L.; Kavraki, L.E.; Mikos, A.G. (2023). “Editorial for Special Issue on Machine Learning in Tissue Engineering.” Tissue Engineering Part A. DOI: 10.1089/ten.tea.2022.29038.editorial.

Guo, J.L.; Longaker, M.T. (2022). “Bioprinted Hydrogels for Fibrosis and Wound Healing: Treatment and Modeling.” Gels. DOI: 10.3390/gels9010019.

Foster, D.S.; Januszyk, M.; Delitto, D.J.; Yost, K.E.; Griffin, M.; Guo, J.L.; Guardino, N.J.; Delitto, A.E.; Chinta, M.; Burcham, A.R.; Nguyen, A.T.; Bauer-Rowe, K.E.; Titan, A.L.; Salhotra, A.; Jones, R.E.; da Silva, O.; Lindsay, H.G.; Berry, C.E.; Chen, K.; Henn, D.; Mascharak, S.; Talbott, H.E.; Kim, A.; Nosrati, F.; Sivaraj, D.; Ransom, R.C.; Matthews, M.; Khan, A.; Wagh, D.; Coller, J.; Gurtner, G.C.; Wan, D.C.; Wapnir, I.L.; Chang, H.Y.; Norton, J.A.; Longaker, M.T. (2022). “Multiomic Analysis Reveals Conservation of Cancer-Associated Fibroblast Phenotypes Across Species and Tissue of Origin.” Cancer Cell. DOI: 10.1016/j.ccell.2022.09.015.

Lintel, H.; Abbas, D.B.; Mackay, D.J.; Griffin, M.; Lavin, C.V.; Berry, C.E.; Guardino, N.J.; Guo, J.L.; Momeni, A.; Mackay, D.R.; Longaker, M.T.; Wan, D.C. (2022). “Topical Vanadate Improves Tensile Strength and Alters Collagen Organization of Excisional Wounds in a Mouse Model.” Wound Repair and Regeneration. DOI: 10.1111/wrr.13062.

Berry, C.E.; Abbas, D.B.; Lintel, H.A.; Churukian, A.A.; Griffin, M.; Guo, J.L.; Cotterell, A.C.; Parker, J.B.L.; Downer, M.A.; Longaker, M.T.; Wan, D.C. (2022). “Adipose-Derived Stromal Cell-Based Therapies for Radiation-Induced Fibrosis.” Advances in Wound Care. DOI: 10.1089/wound.2022.0103.

Guo, J.L.; Januszyk, M; Longaker, M.T. (2022). “Machine Learning in Tissue Engineering.” Tissue Engineering Part A. DOI: 10.1089/ten.TEA.2022.0128.

Lintel, H; Abbas, D.B.; Lavin, C.V.; Griffin, M.F.; Guo, J.L.; Guardino, N.; Churukian, A.; Gurtner, G.C.; Momeni, A.; Longaker, M.T.; Wan, D.C. (2022). “Transdermal Deferoxamine Administration Improves Excisional Wound Healing in Chronically Irradiated Murine Skin.” Journal of Translational Medicine. DOI: 10.1186/s12967-022-03479-4.

Abbas, D.B.; Lintel, H; Griffin, M.F.; Guardino, N.J.; Guo, J.L.; Spielman, A.F.; Cotterell, A.C.; Parker, J.B.L.; Januszyk, M; Wan, D.C. (2022). “Tension Offloading Improves Cutaneous Scar Formation in Achilles Tendon Repair.” Journal of Surgical Case Reports. DOI: 10.1093/jscr/rjac066.

Pearce, H.A.; Swain, J.W.R.; Victor, L.H.; Hogan, K.J.; Jiang, E.Y.; Bedell, M.L.; Navara, A.M.; Farsheed, A.; Kim, Y.S.; Guo, J.L.; Hartgerink, J.D.; Grande-Allen, K.J.; Mikos, A.G. (2022). “Thermogelling Hydrogel Charge and Lower Critical Solution Temperature Influence Cellular Infiltration and Tissue Integration in an Ex Vivo Cartilage Explant Model.” Journal of Biomedical Materials Research Part A. DOI: 10.1002/jbm.a.37441.

Pearce, H.A.; Jiang, E.Y.; Swain, J.W.R.; Navara, A.M.; Guo, J.L.; Kim, Y.S.; Woehr, A.; Hartgerink, J.D.; Mikos, A.G. (2021). “Evaluating the Physicochemical Effects of Conjugating Peptides into Thermogelling Hydrogels for Regenerative Biomaterials Applications.” Regenerative Biomaterials. DOI: 10.1093/rb/rbab073.

Navara, A.M.; Kim, Y.S.; Xu, Y.; Crafton, C.L.; Diba, M.; Guo, J.L.; Mikos, A.G. (2021). “A Dual-Gelling Poly(N-isopropylacrylamide)-Based Ink and Thermoreversible Poloxamer Support Bath for High-Resolution Bioprinting.” Bioactive Materials. DOI: 10.1016/j.bioactmat.2021.11.016.

Kim, Y.S.; Mehta, S.M.; Guo, J.L.; Pearce, H.A.; Smith, B.T.; Watson, E.; Koons, G.L.; Navara, A.M.; Lam, J.; Grande-Allen, K.J.; Mikos, A.G. (2021). “Evaluation of Tissue Integration of Injectable, Cell-Laden Hydrogels of Cocultures of Mesenchymal Stem Cells and Articular Chondrocytes with an Ex Vivo Cartilage Explant Model.” Biotechnology & Bioengineering. DOI: 10.1002/bit.27804.

Guo, J.L.†; Kim, Y.S.†; Koons, G.L.; Lam, J.; Navara, A.M.; Barrios, S.B.; Xie, V.Y.; Watson, E.; Smith, B.T.; Pearce, H.A.; Orchard, E.A.; van den Beucken, J.J.J.P; Jansen, J.A.; Wong, M.E.; Mikos, A.G. (2021). “Bilayered, Peptide-Biofunctionalized Hydrogels for In Vivo Osteochondral Tissue Repair.” Acta Biomaterialia. DOI: 10.1016/j.actbio.2021.04.038.

Guo, J.L.; Diaz-Gomez, L.; Xie, V.Y.; Bittner, S.M.; Jiang, E.Y.; Wang, B.; Mikos, A.G. (2021). “Three-Dimensional Printing of Click Functionalized, Peptide Patterned Scaffolds for Osteochondral Tissue Engineering.” Bioprinting. DOI: 10.1016/j.bprint.2021.e00136.

Bittner, S.M.; Pearce, H.A.; Hogan, K.J.; Smoak, M.M.; Guo, J.L.; Melchiorri, A.J.; Scott, D.W.; Mikos, A. G. (2021). “Swelling Behaviors of 3D Printed Hydrogel and Hydrogel-Microcarrier Composite Scaffolds.” Tissue Engineering Part A. DOI: 10.1089/ten.tea.2020.0377.

Guo, J.L. †; Kim, Y.S. †; Orchard, E.A.; van den Beucken, J.J.J.P; Jansen, J.A.; Wong, M.E.; Mikos, A.G. (2020). “A Rabbit Femoral Condyle Defect Model for Assessment of Osteochondral Tissue Regeneration.” Tissue Engineering Part C: Methods. DOI: 10.1089/ten.TEC.2020.0261.

Kim, Y.S.; Chien, A.J.; Guo, J.L.; Smith, B.T.; Watson, E.; Pearce, H.A.; Koons, G.L.; Navara, A.M.; Lam, J.; Scott, D.W.; Grande-Allen, K.J.; Mikos, A.G. (2020). “Chondrogenesis of Cocultures of Mesenchymal Stem Cells and Articular Chondrocytes in Poly(L-Lysine)-Loaded Hydrogels.” Journal of Controlled Release. DOI: 10.1016/j.jconrel.2020.09.048.

Guo, J.L.; Li, A.; Kim, Y.S.; Xie, V.Y.; Smith, B.T.; Watson, E.; Bao, G.; Mikos, A.G. (2020). “Click Functionalized, Tissue-Specific Hydrogels for Osteochondral Tissue Engineering.” Journal of Biomedical Materials Research Part A. DOI: 10.1002/jbm.a.36848.

Kim, Y.S.; Guo, J.L.; Lam, J.; Grande-Allen, K.J.; Engel, P.; Mikos, A.G. (2019). “Synthesis of Injectable, Thermally Responsive, Chondroitin Sulfate-Cross-Linked Poly(N-isopropylacrylamide) Hydrogels.” ACS Biomaterials Science & Engineering. DOI: 10.1021/acsbiomaterials.9b01450.

Guo, J.L.†; Kim, Y.S.†; Mikos, A.G. (2019). “Biomacromolecules for Tissue Engineering: Emerging Biomimetic Strategies.” Biomacromolecules. DOI: 10.1021/acs.biomac.9b00792.

Du, Y.†; Guo, J.L.†; Wang, J.; Mikos, A.G.; Zhang, S. (2019). “Hierarchically Designed Bone Scaffolds: From Internal Cues to External Stimuli.” Biomaterials. DOI: 10.1016/j.biomaterials.2019.119334.

Guo, J.L.; Kim, Y.S.; Xie, V.Y.; Smith, B.T.; Watson, E.; Lam, J.; Pearce, H.A.; Engel, P.S.; Mikos, A.G. (2019). “Modular, Tissue-Specific, and Biodegradable Hydrogel Cross-Linkers for Tissue Engineering.” Science Advances. DOI: 10.1126/sciadv.aaw7396.
Covered on Rice University News, Texas Medical Center News.

Bittner, S. M.†; Guo, J. L.†; Mikos, A. G. (2018). “Spatiotemporal Control of Growth Factors in Three-Dimensional Printed Scaffolds.” Bioprinting. DOI: 10.1016/j.bprint.2018.e00032.

Yang, J.; Guo, J. L.; Mikos, A. G.; He, C.; Cheng, G. (2018). “Material Processing and Design of Biodegradable Metal Matrix Composites for Biomedical Applications.” Annals of Biomedical Engineering. DOI: 10.1007/s10439-018-2058-y.

Bittner, S. M.†; Guo, J. L.†; Melchiorri, A.; Mikos, A. G. (2018). “Three-Dimensional Printing of Multilayered Tissue Engineering Scaffolds.” Materials Today. DOI: 10.1016/j.mattod.2018.02.006.

Kuang, J.; Guo, J. L.; Messersmith, P. B. (2014). “High Ionic Strength Formation of DOPA-Melanin Coating for Loading and Release of Cationic Antimicrobial Compounds.” Advanced Materials Interfaces. DOI: 10.1002/admi.201400145.

Book Chapters
Majid, M.†; Guo, J.L.†; Kim, Y.S.; Melchiorri, A.J.; Mikos, A.G. (2021). “Chapter 11: Bioprinting Hydrogels and Tissue Engineering.” Injectable Hydrogels for 3D Bioprinting. Royal Society of Chemistry. DOI: 10.1039/9781839163975-00292.

Bedell, M.L.†; Guo, J.L.†; Xie, V.Y.; Navara, A.M.; Mikos, A.G. (2020). “Chapter 17: Polymer Scaffold Fabrication.” Principles of Tissue Engineering (5th ed.). Academic Press. DOI: 10.1016/B978-0-12-818422-6.00018-6.

Guo, J. L.†; Piepergerdes, T.C.†; Mikos, A.G. (2020). “Chapter 6: Bone Graft Engineering: Composite Scaffolds.” Dental Implants and Bone Grafts: Materials and Biological Issues (1st ed.). Woodhead Publishing. DOI: 10.1016/B978-0-08-102478-2.00007-6.

Patents
Longaker, M.T.; Appel, E.A.; Foster, D.S.; Guo, J.L.; Delitto, D.J.; Meany, E.L.; Norton, J.A.; Song, R. (2024). “Encapsulation and Local Delivery of Inhibitors of the Activator Protein 1 (AP-1) for Preventing Adhesions.” US Patent App. 63/547,764.

Guo, J.L.; Mascharak, S.; Foster, D.S.; Norton, J.A.; Longaker, M.T. (2023). “Systems and Methods for Personalized Treatment of Tumors.” US Patent App. 63/264,159.

Mikos, A.G.; Guo, J.L; Diaz-Gomez, L.A.; Melchiorri, A.J.; Elizondo, M.E.; Koons, G.L.; Kontoyiannis, P.D. (2023). “Extrusion Printing of Biocompatible Scaffolds.” US Patent App. 17/904,266.